Top Hotels in Florence Alabama for an Unforgettable Stay

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Nestled along the banks of the Tennessee River, Florence is a hidden gem in the American South that beckons travelers with its rich history, vibrant culture, and warm southern hospitality. This charming city, a cornerstone of the Shoals area, offers an array of accommodations, ensuring visitors can find the perfect base to explore all the local treasures. From luxurious boutiques to cozy inns, the variety of hotels in Florence caters to every preference and budget, making it an ideal destination for both leisure and business travelers alike.

The selection of hotels in Florence is thoughtfully designed to enhance your visit, providing not just a place to stay, but an experience that complements the city's unique character. Whether you're drawn to the historical downtown area, with its shops and eateries, or the serene landscapes along the river, there's a hotel in Florence positioned to give you easy access to your chosen attractions. Recommendations for accommodations come with insights into local entertainment, dining, and historical sites, ensuring guests encounter the very essence of Florence during their stay.

Understanding the importance of comfort and convenience, hotels in Florence come equipped with a range of amenities to suit every need. From swimming pools for a refreshing dip on a hot day to conference rooms for business meetings, these hotels are replete with features that promise a satisfying and memorable visit. By choosing the right hotel, you're not just booking a room; you're unlocking the door to an immersive Florence experience, highlighting the best the city has to offer and leaving you with lasting memories of your time in this enchanting part of the United States.

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Our Top 6

(Sorted by rating & number of reviews)

1. Hampton Inn & Suites-Florence Downtown
2. Holiday Inn Express Florence Northeast, An Ihg Hotel
3. Marriott Shoals Hotel & Spa
4. Residence Inn By Marriott Florence
5. Quality Inn Florence Muscle Shoals
6. Gunrunner Boutique Hotel

Luxury and Spa Resorts in Florence, Alabama

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Florence
Oct 30, 2025 - Oct 31, 2025

Hampton Inn & Suites-Florence Downtown

8.6

Good

(189 Reviews)

+ 132 photos
The Hampton Inn & Suites Florence-Downtown offers an ideal mix of comfort and convenience for outdoor enthusiasts. Located in the heart of Florence, it provides guests with easy access to the city's vibrant downtown area, as well as quick routes to outdoor attractions like McFarland Park and Florence Harbor. Guests can start the day with a complimentary hot breakfast before setting off on their adventures. The hotel also features a fitness center and refined rooms, ensuring a relaxing stay after a day of exploration. Its proximity to the Tennessee River makes it particularly appealing for those interested in water-based activities. The Hampton Inn & Suites Florence-Downtown is a welcome haven for guests looking to enjoy both the urban charm and outdoor splendors of Florence.
Address: 505 South Court Street
Rating: Good 8.6 (189 Reviews)
Rooms: 88
Price: From 116$

Holiday Inn Express Florence Northeast, An Ihg Hotel

8.3

Good

(333 Reviews)

+ 45 photos
The Holiday Inn Express Florence Northeast offers families the perfect blend of comfort, convenience, and value. With spacious rooms equipped with modern amenities, families can relax in a welcoming environment after a day of exploring. The complimentary breakfast buffet is a hit among guests of all ages, featuring a variety of options to start the day right. The indoor pool provides year-round entertainment for kids, while the fitness center allows parents to stay on top of their workout routines. Situated near Florence's main attractions, the hotel ensures families have easy access to the best the city has to offer. The Holiday Inn Express Florence Northeast is committed to making your family's stay as enjoyable and hassle-free as possible.
Address: 180 Etta Gray Street
Rating: Good 8.3 (333 Reviews)
Rooms: 79
Price: From 139$

Business-Friendly Hotels in Florence, Alabama

Business travelers require accommodations that not only provide comfort but also facilitate work needs with ease. In this section, we spotlight hotels in Florence that are equipped with amenities such as high-speed internet, business centers, and meeting rooms. These hotels cater to the efficiency and convenience demanded by professionals. With strategic locations that provide easy access to local business districts and airports, these selections ensure a productive and stress-free stay.

Marriott Shoals Hotel & Spa

8.7

Good

(242 Reviews)

+ 147 photos
Nestled atop the rolling hills overlooking the Tennessee River, the Marriott Shoals Hotel & Spa is a sanctuary of peace and luxury. With its beautifully appointed rooms, each offering breathtaking views, guests are invited into a world of elegance and serenity. The hotel boasts a full-service spa, where expert therapists provide a range of rejuvenating treatments designed to relax and invigorate. The outdoor pool and hot tub are perfect for unwinding while enjoying the scenic surroundings. Dining at the hotel's signature restaurant, which features locally sourced ingredients, is an experience in itself. Furthermore, the Marriott Shoals Hotel & Spa is renowned for its exceptional service, ensuring every aspect of your stay is nothing short of extraordinary.
Address: 10 Hightower Place
Rating: Good 8.7 (242 Reviews)
Rooms: 199
Price: From 143$

Residence Inn By Marriott Florence

8.4

Good

(62 Reviews)

+ 27 photos
The Residence Inn by Marriott Florence stands out as an ideal choice for business travelers requiring extended stays. Each suite is designed with spaciously separated living, working, and sleeping areas, equipped with full kitchens and ergonomic workstations. The hotel offers complimentary Wi-Fi throughout the property, and a business center is available for guests’ professional needs. Guests can start their day with a hot breakfast and unwind in the evening at the social mixers, offering light fare and refreshments. Its proximity to local businesses and the University of North Alabama makes it a convenient hub for professionals. The commitment to comfort and functionality makes the Residence Inn by Marriott Florence a top selection for those traveling on business.
Address: 1000 Sweetwater Avenue
Rating: Good 8.4 (62 Reviews)
Rooms: 110
Price: From 113$

Adventure and Outdoor Hotels in Florence, Alabama

Adventurers and nature lovers looking to explore Florence beautiful landscapes will find suitable accommodations in this section. These hotels are conveniently located near parks, rivers, and outdoor activity centers, making it easy to embark on an adventure. Whether it’s fishing on the Tennessee River, hiking through majestic trails, or enjoying a round of golf, these accommodations provide easy access to nature's playground while offering a cozy retreat at the end of an active day.

Quality Inn Florence Muscle Shoals

6.3

Good

(179 Reviews)

+ 67 photos
The Quality Inn Florence Muscle Shoals is a testament to the fact that affordable lodging doesn't have to skimp on comfort or convenience. Guests are treated to comfortable rooms, each equipped with essential amenities like free Wi-Fi, coffee makers, and premium bedding. The outdoor pool is a welcome respite on warm days, while the complimentary breakfast ensures a great start to your morning. Located within easy reach of local attractions and dining options, the hotel is an ideal base for travelers looking to explore Florence without breaking the bank. The friendly staff and well-maintained facilities at the Quality Inn Florence Muscle Shoals make it a top choice for budget-conscious travelers seeking value and quality.
Address: 150 Etta Gray Drive
Rating: Good 6.3 (179 Reviews)
Rooms: 47
Price: From 75$

Gunrunner Boutique Hotel

9.3

Good

(29 Reviews)

+ 65 photos
The Gunrunner Boutique Hotel offers a rare blend of privacy, luxury, and artistic flair in the lively heart of downtown Florence. Each of the ten uniquely themed suites showcases an aspect of Alabama's rich cultural and historical heritage, with spacious layouts and custom furnishings. Guests can enjoy the exclusivity of private access to the hotel, ensuring a sense of retreat and relaxation. The welcoming bar area and lounge invite guests to mingle, while the rooftop boasts panoramic views of the city. Renowned for its attention to detail, the Gunrunner Boutique Hotel creates a personalized and unforgettable lodging experience. The hotel's commitment to celebrating local art and craftsmanship makes it a standout choice for discerning travelers.
Address: 310 E Tennessee St
Rating: Good 9.3 (29 Reviews)
Rooms: 34
Price: From 277$